Georgiana Luppens

Myeloid Dysplastic Syndrome (MDS) is a type of blood cancer where patients have troubles generating mature blood cells. In pediatrics, it accounts between 5 and 10% of all hematological malignancies. The underlying molecular mechanisms of MDS are still unknown. However, we see that a large group of pediatric MDS patients display a monosomy 7. In my master’s project I will attempt to mimic this monosomy 7 in vitro and I will hope to unravel how this could contribute to the onset of MDS.