Just before Christmas on December 21st, our PhD student Flavia Peci defended her thesis "Genomic Safety of Transplantation; characterising the Mutational Consequences of Treatment in Hematopoietic Stem Cells".
In our lab we developed the computational PTA Analysis Toolbox (PTATO) that can effectively filter artifacts from PTA-based WGS data, enabling accurate analyses of somatic mutations in single cells at nucleotide resolution.
Mitochondria in normal cells accumulate mutations with age. Most mitochondrial mutations in cancer result from healthy mutation accumulation. Cancer therapies do not result in many mitochondrial mutations
Today the NYSCF Robertson Stem Cell Investigator Award was awarded in New York today to Dr. Ruben van Boxtel. Van Boxtel, will use the award to accelerate his research on the role of stem cells in the development and eventual prevention of adverse late effects in children cured of cancer.
Each year, the graduate school Cancer, Stem cells and Developmental biology gives an award to the PhD student with the best publication of that year. Today, the award was given to Jurrian de Kanter from our group for his two publications on the damaging effects of treatment in children with cancer.
During a 3 months-long program six teams were guided through setting up a venture plan, which takes an animal free scientific breakthrough in the life sciences and transformed it into a solid business case.