Co-culture of intestinal organoids with a colibactin-producing pks+ E. coli strain (EcC) revealed mutational signatures also found in colorectal cancer (CRC).
Read MoreCo-culture of intestinal organoids with a colibactin-producing pks+ E. coli strain (EcC) revealed mutational signatures also found in colorectal cancer (CRC).
Read MoreJust before Christmas on December 21st, our PhD student Flavia Peci defended her thesis "Genomic Safety of Transplantation; characterising the Mutational Consequences of Treatment in Hematopoietic Stem Cells".
Read MoreTuesday our PhD student Eline Bertrums defended her thesis defence entitled: "The Clonal Dynamics underlying the genesis and regression of myeloid disorders", with cum laude.
Read MoreIn our lab we developed the computational PTA Analysis Toolbox (PTATO) that can effectively filter artifacts from PTA-based WGS data, enabling accurate analyses of somatic mutations in single cells at nucleotide resolution.
Read MoreMitochondria in normal cells accumulate mutations with age. Most mitochondrial mutations in cancer result from healthy mutation accumulation. Cancer therapies do not result in many mitochondrial mutations
Read MoreToday the NYSCF Robertson Stem Cell Investigator Award was awarded in New York today to Dr. Ruben van Boxtel. Van Boxtel, will use the award to accelerate his research on the role of stem cells in the development and eventual prevention of adverse late effects in children cured of cancer.
Read MoreVind hier de presentatie van Ruben tijdens het Weekend van de Wetenschap 2022.
Read MoreEach year, the graduate school Cancer, Stem cells and Developmental biology gives an award to the PhD student with the best publication of that year. Today, the award was given to Jurrian de Kanter from our group for his two publications on the damaging effects of treatment in children with cancer.
Read MoreElevated mutational age in blood of children treated for cancer contributes to therapy-related myeloid neoplasms
Read More"The beginning of a new life: characterising somatic mutation accumulation in fetal stem cells"
Read MoreWhole-genome sequencing and mutational analysis of human cord-blood derived stem and progenitor cells
Read MoreDuring a 3 months-long program six teams were guided through setting up a venture plan, which takes an animal free scientific breakthrough in the life sciences and transformed it into a solid business case.
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